Description

3-((3-Deoxycholamidopropyl)Dimethylammonio)-1-Propane is a high-purity, synthetic bile acid derivative widely used as a critical reagent in biochemical and pharmaceutical research. Its primary value lies in its ability to solubilize membrane proteins and lipids, making it essential for studying complex biological systems. This compound is particularly needed by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic sectors for applications requiring gentle yet effective detergency.

Application

• Membrane Protein Solubilization and Stabilization: A key reagent for extracting and maintaining the native structure of integral membrane proteins for structural biology studies (e.g., X-ray crystallography, cryo-EM).
• Lipid Raft Research: Used to isolate and study detergent-resistant membrane microdomains (lipid rafts) crucial for understanding cell signaling and membrane organization.
• Cell Lysis and Organelle Isolation: Employed in buffer formulations for gentle cell disruption and the isolation of functional cellular organelles.
• Pharmaceutical Excipient Development: Investigated for its potential as an absorption enhancer or solubilizing agent in novel drug delivery systems.
• Diagnostic Assay Formulation: Serves as a stabilizing agent in diagnostic kits, particularly those involving membrane-bound antigens or enzymes.
• Biophysical Studies: Utilized in the formation of micelles and mixed micelles for studying lipid-protein interactions and membrane dynamics.

Basic Information

Item	Details
Product Name	3-((3-Deoxycholamidopropyl)Dimethylammonio)-1-Propane
CAS No.	106679-03-2
Molecular Formula	C32H56N2O4
Molecular Weight	532.80 g/mol
Synonyms	CHAPS; 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate; N,N-Dimethyl-3-sulfo-N-[3-(3α,7α,12α-trihydroxy-24-oxocholan-24-yl)aminopropyl]-1-propanaminium hydroxide, inner salt; Zwittergent 3-12; CHAPS Zwitterionic Detergent; 3-(3-Cholamidopropyl)dimethylammonio-1-propanesulfonate; 3-[(3-Cholamidopropyl)dimethylammonio]propanesulfonate
EINECS	Contact for details

Quality Control

Our 3-((3-Deoxycholamidopropyl)Dimethylammonio)-1-Propane is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and critical micelle concentration (CMC) verification. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	6-10 mM (in water at 25°C)
pH (1% Solution)	5.0 - 7.0
UV Absorbance (280 nm)	Passes test
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.