Description

L-Ile-4-(4-Amino-2,5-Cyclohexadien-1-Yl)-L-Abu-Oh is a specialized, non-proteinogenic amino acid derivative featuring a unique cyclohexadienyl moiety. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a sophisticated building block for novel peptide-based therapeutics and diagnostic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex bioactive molecules, targeted drug delivery systems, and high-value chemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide drugs and enzyme inhibitors.
• Bioconjugation Chemistry: Serves as a specialized linker or spacer molecule for attaching payloads in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Used as a building block for synthesizing activity-based probes (ABPs) and other tools to study enzyme function and protein-protein interactions.
• Peptidomimetic Design: Integral for creating constrained peptide analogs and peptidomimetics with enhanced metabolic stability and binding affinity.
• Advanced Material Science: Potential applications in the development of functionalized polymers and smart biomaterials with specific molecular recognition properties.

Basic Information

Product Name	L-Ile-4-(4-Amino-2,5-Cyclohexadien-1-Yl)-L-Abu-Oh
CAS No.	96717-73-6
Molecular Formula	C16H27N3O3
Molecular Weight	309.41 g/mol
Synonyms	4-(4-Amino-2,5-cyclohexadien-1-yl)-L-isoleucyl-L-2-aminobutanoic acid; L-Ile-4-(4-Amino-2,5-Cyclohexadienyl)-L-Abu-OH; (2S)-2-[[(2S,3S)-2-[[4-Amino-2,5-cyclohexadien-1-yl]methyl]-3-methylpentanoyl]amino]butanoic acid; Cyclohexadienyl Amino Acid Derivative; Ile-Abu Cyclohexadienyl Derivative; 96717-73-6; Amino Acid Conjugate with Cyclohexadiene
EINECS	Contact for details

Quality Control

Our L-Ile-4-(4-Amino-2,5-Cyclohexadien-1-Yl)-L-Abu-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and comprehensive spectroscopic identification (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications. Our commitment is to deliver material of the highest chemical purity and structural integrity for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.