Description

Sincalide, Pglu- is a synthetic peptide analog of the C-terminal octapeptide of cholecystokinin (CCK-8). This compound is a potent diagnostic and research agent used to stimulate gallbladder contraction and pancreatic secretion. It is essential for pharmaceutical research, diagnostic imaging, and the development of gastrointestinal therapeutics. The product is supplied under the CAS registry number 96693-35-5.

Application

• Diagnostic Imaging: Used as a diagnostic agent in cholescintigraphy (HIDA scans) to assess gallbladder ejection fraction and diagnose biliary dyskinesia.
• Pharmaceutical Research: Serves as a critical reference standard and active pharmaceutical ingredient (API) in the development of gastrointestinal drugs.
• Physiological Studies: Employed in preclinical and clinical research to study cholecystokinin receptor (CCK) function, pancreatic secretion, and gut-brain axis signaling.
• Quality Control: Utilized as a high-purity analytical standard in HPLC and other chromatographic methods for quality assurance in peptide manufacturing.

Basic Information

Product Name	Sincalide, Pglu-
CAS No.	96693-35-5
Molecular Formula	C49H62N10O16S2
Molecular Weight	1143.2 g/mol
Synonyms	Sincalide; CCK-8; Cholecystokinin Octapeptide; SQ 19,844; Kinevac; Sincalide Acetate; Cholecystokinin (26-33), sulfated; CCK (26-33), sulfated
EINECS	Contact for details

Quality Control

Our Sincalide, Pglu- is manufactured under strict quality systems suitable for pharmaceutical research and diagnostic applications. Each batch undergoes rigorous analytical testing, including HPLC for purity, peptide content determination, and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to ensure traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term stability, consider storage at -20°C under desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Biological Activity	Assayed (upon request)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.