Description

Tinzaparin Sodium is a low molecular weight heparin (LMWH) derived from porcine mucosal heparin, widely used as an anticoagulant and antithrombotic agent. Its primary value lies in its predictable pharmacokinetic profile and reduced risk of heparin-induced thrombocytopenia compared to unfractionated heparin, making it a critical component in modern therapeutic protocols. This product is essential for pharmaceutical manufacturers and research institutions developing parenteral formulations for the prevention and treatment of deep vein thrombosis (DVT) and other thromboembolic disorders.

Application

• Anticoagulant Therapy: Primary active pharmaceutical ingredient (API) in injectable formulations for the prevention and treatment of venous thromboembolism (VTE).
• Surgical Prophylaxis: Used to prevent blood clot formation in patients undergoing major orthopedic surgery, such as hip or knee replacement.
• Medical Prophylaxis: Administration to immobilized medical patients to reduce the risk of DVT and pulmonary embolism (PE).
• Research & Development: Critical reference standard and biochemical reagent in hematology and coagulation studies for developing new antithrombotic agents.
• Biosimilar Development: Serves as a key comparator in the development and regulatory filing of biosimilar low molecular weight heparins.

Basic Information

Product Name	Tinzaparin Sodium
CAS No.	12656-11-0
Molecular Formula	Contact for details
Molecular Weight	Average MW ~ 4500-7500 Da (Contact for specific grade details)
Synonyms	Tinzaparin; Tinzaparin Sodium Salt; Innohep (Trade Name); Logiparin (Trade Name); Heparin, Low-Molecular-Weight, Tinzaparin; Sodium Tinzaparin; LMWH (Tinzaparin); Anticoagulant Tinzaparin
EINECS	Contact for details

Quality Control

Our Tinzaparin Sodium is manufactured and tested under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical actives. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as anti-Factor Xa and anti-Factor IIa activity, molecular weight distribution, and purity. We support compliance with major pharmacopoeial standards, including USP and EP monographs for Heparin Sodium, Low-Molecular-Mass.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, ideally between 15°C and 25°C (59°F and 77°F). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
pH (Solution)	5.5 - 7.5
Anti-Factor Xa Activity	Contact for details
Anti-Factor IIa Activity	Contact for details
Anti-Factor Xa / IIa Ratio	Contact for details
Molecular Weight Distribution	Meets pharmacopoeial requirements
Protein	≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.1 IU/anti-Xa IU
Assay (Dry Basis)	90.0% - 110.0% of labeled anti-Factor Xa activity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.