Description

Dipyridamole Tri(Diethanolamine) is a pharmaceutical-grade complex of the antiplatelet agent dipyridamole with diethanolamine, enhancing its solubility and stability for advanced drug formulations. This compound is critical for ensuring consistent bioavailability and therapeutic efficacy in finished pharmaceutical products. It is primarily required by manufacturers in the pharmaceutical industry for the development and production of cardiovascular medications, diagnostic agents, and other specialized therapeutic formulations.

Application

• Pharmaceutical Active Ingredient: Primary use as an antiplatelet agent in the formulation of cardiovascular drugs to prevent blood clots.
• Diagnostic Agent Production: Used in the manufacture of diagnostic pharmaceuticals for cardiac stress tests (e.g., Persantine®).
• Solubility-Enhanced Formulations: The tri(diethanolamine) complex improves the aqueous solubility of dipyridamole for injectable and oral liquid dosage forms.
• Research & Development: Serves as a key intermediate and reference standard in pharmaceutical R&D for new anti-thrombotic therapies.
• Generic Drug Manufacturing: Essential for producing generic versions of dipyridamole-based medications, ensuring bioequivalence.
• Controlled-Release Drug Delivery Systems: Incorporated into advanced delivery systems that require precise release profiles of the active pharmaceutical ingredient (API).

Basic Information

Product Name	Dipyridamole Tri(Diethanolamine)
CAS No.	16908-47-7
Molecular Formula	C31H54N8O9
Molecular Weight	682.82 g/mol
Synonyms	Dipyridamole Diethanolamine Salt; Dipyridamole DEA Complex; Persantine Diethanolamine; 2,2',2'',2''',2'''',2'''''-((((2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(azanetriyl))bis(1,3,8,10-tetraazatricyclo[7.4.0.0³,⁷]trideca-1,3,5,7,9,11-hexaene-6,12-diyl))hexakis(ethanol); Dipyridamole Triethanolamine Salt (common misnomer); Dipyridamole Solubilized Form; Coronary Vasodilator Complex.
EINECS	Contact for details

Quality Control

Our Dipyridamole Tri(Diethanolamine) is manufactured under strict quality management systems, targeting compliance with ICH Q7, GMP, and relevant pharmacopoeial standards (e.g., USP, EP). Each batch undergoes rigorous analytical testing including identity, purity, and impurity profile analysis. Certificates of Analysis (COA) detailing all test results are available upon request to ensure full traceability and regulatory support for your pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Yellow to greenish-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.