Description

2-Methyl-Dl-Tyrosine is a synthetic, non-proteinogenic amino acid derivative, serving as a key chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a methyl-substituted tyrosine scaffold, enabling the study of structure-activity relationships and the development of novel compounds with modified biological properties. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for applications in peptide modification, medicinal chemistry, and biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic pathways.
• Peptide Chemistry & Research: Used to incorporate modified tyrosine residues into synthetic peptides to alter their stability, receptor binding affinity, or metabolic profile.
• Medicinal Chemistry & SAR Studies: Serves as a standard or reference compound for structure-activity relationship (SAR) studies to optimize lead compounds.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies, particularly those involving tyrosine kinases, decarboxylases, or hydroxylases.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex organic molecules and natural product analogs.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	2-Methyl-Dl-Tyrosine
CAS No.	96646-27-4
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	2-Methyltyrosine; DL-2-Methyltyrosine; α-Methyl-DL-tyrosine; (±)-2-Methyltyrosine; 3-(4-Hydroxyphenyl)-2-methylalanine; AMT; 2-Methyl-3-(4-hydroxyphenyl)alanine; α-Methyl-p-tyrosine (common research name)
EINECS	Contact for details

Quality Control

Our 2-Methyl-Dl-Tyrosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific results for each batch are available upon request. We adhere to cGMP principles where applicable to ensure traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific rotation provided on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.