Description

(Tyr9)-Cholecystokinin Octapeptide (Sulfated) CAS NO 96607-61-3 is a synthetic, sulfated analog of the endogenous peptide hormone cholecystokinin (CCK), specifically mimicking the biologically active C-terminal octapeptide fragment. This high-purity peptide is critical for research and development in neuroscience, gastroenterology, and endocrinology, where precise receptor binding and signaling studies are paramount. It is an essential tool for pharmaceutical researchers, academic institutions, and diagnostic manufacturers investigating CCK receptor function, drug discovery, and metabolic pathways.

Application

• Neuroscience Research: Used as a selective agonist for CCK receptors (CCK1 and CCK2) to study anxiety, satiety, pain modulation, and dopaminergic interactions in the central nervous system.
• Gastrointestinal Physiology Studies: Employed to investigate pancreatic enzyme secretion, gallbladder contraction, gut motility, and as a model for studying digestive hormone action.
• Drug Discovery & Screening: Serves as a reference standard and pharmacological tool in high-throughput screening (HTS) assays to identify and characterize novel CCK receptor antagonists or agonists.
• Biochemical Assay Development: Utilized in the development and validation of radioimmunoassays (RIA), ELISA kits, and other diagnostic tests for measuring CCK levels.
• Academic & Pharmaceutical R&D: A key reagent for basic research into hormone-receptor interactions, signal transduction mechanisms, and peptide structure-activity relationships (SAR).
• Metabolic Disorder Research: Applied in studies exploring the role of CCK in obesity, appetite regulation, and insulin secretion.

Basic Information

Product Name	(Tyr9)-Cholecystokinin Octapeptide (Sulfated)
CAS No.	96607-61-3
Molecular Formula	C49H62N10O16S2
Molecular Weight	1143.2 g/mol
Synonyms	CCK-8 (sulfated); Cholecystokinin Octapeptide, Sulfated; Sincalide; CCK-8S; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; SQ 19,844; CCK Octapeptide; Tyrosyl-sulfated CCK (26-33); CCK (26-33), sulfated
EINECS	Contact for details

Quality Control

Our (Tyr9)-Cholecystokinin Octapeptide (Sulfated) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. Comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.