Description

6-Bromopyrazolo[3,4-D]Pyrimidin-4(5H)-One is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent kinase inhibitors (e.g., JAK, BTK inhibitors) and other small molecule drug candidates.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a scaffold for developing selective enzyme inhibitors and molecular probes to study biological pathways.
• Fine Chemical Synthesis: A versatile building block for constructing complex pyrazolopyrimidine-based compounds with tailored functionalities.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	6-Bromopyrazolo[3,4-D]Pyrimidin-4(5H)-One
CAS No.	96555-35-0
Molecular Formula	C5H3BrN4O
Molecular Weight	214.99 g/mol
Synonyms	6-Bromo-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one; 6-Bromo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Bromo-4,5-dihydropyrazolo[3,4-d]pyrimidin-4(1H)-one; 6-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one; 6-Bromopyrazolo[3,4-d]pyrimidin-4-ol; 6-Bromo-4-hydroxy-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 6-Bromopyrazolo[3,4-D]Pyrimidin-4(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.