Description

n-Glycylglycyl-S-Acetylcysteamine Trifluoroacetate is a specialized, high-purity peptide derivative used as a critical building block and reagent in advanced chemical synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds for developing novel pharmaceuticals and biochemical probes. It is primarily utilized in the synthesis of enzyme inhibitors, prodrugs, and as a key intermediate in peptide and protein conjugation strategies within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor research.
• Bioconjugation Reagent: Used for site-specific modification of peptides, proteins, and antibodies to create targeted drug conjugates or diagnostic agents.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Prodrug Development: Utilized in the design of prodrugs where the S-acetylcysteamine moiety acts as a cleavable linker for controlled drug release.
• Peptide Synthesis: Acts as a protected cysteine derivative or a specialized dipeptide fragment in solid-phase and solution-phase peptide synthesis.
• Chemical Biology Tool: Employed in the development of activity-based probes (ABPs) for labeling and studying enzyme function in complex biological systems.

Basic Information

Product Name	n-Glycylglycyl-S-Acetylcysteamine Trifluoroacetate
CAS No.	96538-33-9
Molecular Formula	C9H15N3O4S • C2HF3O2
Molecular Weight	Contact for details
Synonyms	Gly-Gly-S-acetylcysteamine TFA salt; N-(2-[(Acetylsulfanyl)ethyl]carbamoyl)glycylglycine trifluoroacetate; Glycylglycyl-S-acetyl-2-aminoethanethiol TFA; S-Acetylcysteamine glycylglycine derivative; H-Gly-Gly-SC2H4SAc•TFA; 2-[[2-[(2-Acetylsulfanylethyl)amino]-2-oxoethyl]amino]-2-oxoacetic acid trifluoroacetate; Peptide conjugation reagent 96538-33-9
EINECS	Contact for details

Quality Control

Our n-Glycylglycyl-S-Acetylcysteamine Trifluoroacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.