Description

2-Chloro-3-Fluorobenzaldehyde is a versatile halogenated benzaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a halogenated aromatic core for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro substitution pattern can enhance target binding and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the development of organic electronic materials, such as dyes, pigments, and molecular components for OLEDs.
• Custom Synthesis and R&D: A fundamental reagent for medicinal chemistry programs and contract research organizations (CROs) exploring new chemical space.
• Fluorine Chemistry Building Block: The presence of both chlorine and fluorine makes it a valuable substrate for further selective functionalization in fluorochemical research.

Basic Information

Product Name	2-Chloro-3-Fluorobenzaldehyde
CAS No.	96516-31-3
Molecular Formula	C7H4ClFO
Molecular Weight	158.56 g/mol
Synonyms	2-Chloro-3-fluorobenzaldehyde; 3-Fluoro-2-chlorobenzaldehyde; Benzaldehyde, 2-chloro-3-fluoro-; o-Chloro-m-fluorobenzaldehyde; 2-Chloro-3-fluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluorobenzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider packaging under an inert atmosphere such as nitrogen.

Specification

Item	Specification
Appearance	Colorless to pale yellow crystalline solid or liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.