Description

Gly-Arg-Gly-Asp-Ser (GRGDS) is a synthetic, biologically active pentapeptide sequence that mimics a key cell adhesion motif found in extracellular matrix proteins like fibronectin. This compound is critical for research and development in biomaterials and regenerative medicine due to its specific interaction with integrin receptors. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biomedical engineering, and life science sectors for applications ranging from cell culture to drug delivery systems.

Application

• Biomaterial Functionalization: Coating surfaces of implants, scaffolds, and medical devices to promote specific cell adhesion and tissue integration.
• Cell Culture Research: Used as a bioactive peptide to study cell signaling, migration, and proliferation in vitro, particularly for endothelial, epithelial, and stem cells.
• Drug Delivery Systems: Incorporated into nanoparticles, hydrogels, and liposomes to create targeted delivery platforms that home to specific cell types.
• Tissue Engineering: A key component in the design of synthetic extracellular matrices that guide tissue regeneration and wound healing.
• Inhibitor Studies: Serves as a competitive inhibitor in assays to study integrin-ligand interactions and related biological pathways.
• Diagnostic Development: Potential use in biosensors and diagnostic kits for detecting cell adhesion molecules or specific cell types.

Basic Information

Product Name	Gly-Arg-Gly-Asp-Ser
CAS No.	96426-21-0
Molecular Formula	C19H33N9O9
Molecular Weight	531.52 g/mol
Synonyms	GRGDS Peptide; Arg-Gly-Asp-Ser-Gly; H-Gly-Arg-Gly-Asp-Ser-OH; Fibronectin Cell-Adhesion Peptide; Adhesion Peptide GRGDS; RGD Peptide (Serine variant); Pentapeptide GRGDS; L-Glycyl-L-arginylglycyl-L-α-aspartyl-L-serine
EINECS	Contact for details

Quality Control

Our Gly-Arg-Gly-Asp-Ser is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.