Description

Dermorphin, Arg(2)- is a synthetic heptapeptide analog of the potent opioid peptide dermorphin, featuring an arginine substitution at the second position. This modification is designed to enhance its stability and receptor-binding profile, making it a valuable tool for advanced pharmacological research. It is primarily utilized by research institutions and pharmaceutical developers in the fields of neurobiology, pain management, and opioid receptor studies.

Application

• Neuroscience Research: Used as a selective ligand for studying mu-opioid receptor (MOR) signaling pathways and mechanisms of analgesia.
• Pharmacological Assays: Serves as a reference standard or active agent in in vitro and in vivo assays to evaluate opioid activity and potency.
• Drug Discovery: Acts as a lead compound or molecular scaffold for the development of novel analgesic drugs with potentially improved safety profiles.
• Biochemical Studies: Employed in structure-activity relationship (SAR) studies to understand the impact of specific amino acid substitutions on peptide function.

Basic Information

Product Name	Dermorphin, Arg(2)-
CAS No.	96425-96-6
Molecular Formula	C41H60N14O10
Molecular Weight	909.02 g/mol
Synonyms	H-Tyr-D-Arg-Phe-Gly-Tyr-Pro-Ser-NH2; [D-Arg2]-Dermorphin; Arg2-Dermorphin; Dermorphin (2-D-arginine); Dermorphin, [D-Arg2]-; Tyr-D-Arg-Phe-Gly-Tyr-Pro-Ser-NH2
EINECS	Contact for details

Quality Control

Our Dermorphin, Arg(2)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and residual solvent levels are provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.