Description

Tyrosyl-Arginyl-Phenylalanyl-Alanine is a synthetic tetrapeptide composed of the amino acids tyrosine, arginine, phenylalanine, and alanine. This sequence is of significant interest in biochemical research and pharmaceutical development for studying peptide-protein interactions and biological signaling pathways. It serves as a critical building block for researchers and manufacturers in the life sciences sector, particularly for applications in drug discovery, proteomics, and as a reference standard.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and study of novel therapeutic peptides and peptidomimetics.
• Biochemical Assay Development: Employed as a substrate or inhibitor in enzymatic assays to study protease activity and specificity.
• Proteomics & Cell Signaling Studies: Utilized as a tool to investigate peptide-mediated cell signaling pathways and receptor-ligand interactions.
• Cosmeceutical Formulations: Incorporated into advanced skincare products for its potential bioactive properties related to the constituent amino acids.
• Academic & Institutional Research: Serves as a high-purity chemical for basic scientific research in universities and government laboratories.
• Quality Control & Analytical Standards: Acts as a certified reference material (CRM) for analytical method validation and quality assurance in peptide manufacturing.

Basic Information

Product Name	Tyrosyl-Arginyl-Phenylalanyl-Alanine
CAS No.	96425-84-2
Molecular Formula	C31H43N9O7
Molecular Weight	653.73 g/mol
Synonyms	Tyr-Arg-Phe-Ala; YRFA; L-Tyrosyl-L-arginyl-L-phenylalanyl-L-alanine; H-Tyr-Arg-Phe-Ala-OH; Tetrapeptide YRFA; 4-L-Alanine-9-L-arginine-10-L-phenylalanine-13-L-tyrosine-α-melanocyte-stimulating hormone (4-13); α-MSH (4-13); Melanotropin (4-13)
EINECS	Contact for details

Quality Control

Our Tyrosyl-Arginyl-Phenylalanyl-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); desiccants are recommended for long-term storage. Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.