Description

β-Endorphin, Arg(9,12,24,28,29)- is a synthetic, modified peptide analog of the endogenous neuropeptide β-endorphin, designed for enhanced stability and specific receptor interaction. This compound is critical for advanced research in neurobiology, pain modulation, and the development of novel therapeutic agents targeting opioid pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on central nervous system disorders and analgesic drug discovery.

Application

• Neuroscientific Research: Used as a high-purity reference standard and tool compound for studying endogenous opioid systems, receptor binding assays, and signal transduction mechanisms.
• Analgesic Drug Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the research and development of next-generation, non-addictive pain management therapies.
• Biochemical Assays: Employed in competitive ELISA tests, radioimmunoassays (RIA), and other in vitro diagnostic applications to quantify endorphin levels.
• Cell Culture & Physiology Studies: Applied in experimental models to investigate the effects of opioid peptides on cell proliferation, immune response, and stress physiology.
• Peptide Chemistry & Conjugation: Acts as a base structure for further chemical modification, labeling (e.g., with fluorescent dyes or biotin), and the synthesis of peptide libraries.

Basic Information

Product Name	β-Endorphin, Arg(9,12,24,28,29)-
CAS No.	96420-12-1
Molecular Formula	C164H251N51O46S
Molecular Weight	~3466.1 g/mol
Synonyms	[Arg9,12,24,28,29]-β-Endorphin; β-Endorphin (Arg9,12,24,28,29); Human β-Endorphin analog; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH; Modified β-Endorphin; Opioid peptide analog; β-LPH (61-91), Arg9,12,24,28,29
EINECS	Contact for details

Quality Control

Every batch of our β-Endorphin, Arg(9,12,24,28,29)- is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support its use in critical research and development applications. Certificates of Analysis (COA) detailing purity, identity, and peptide content are available for each lot, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.