Description

β-Endorphin, Cys(11,26),Phe(27), Gly(31)- CAS NO 96407-33-9 is a synthetic, modified peptide analog of the endogenous neuropeptide β-endorphin, engineered for enhanced stability and specific receptor interaction. This compound is critical for advanced research in neurobiology, pain management, and the development of novel therapeutic agents targeting the opioid receptor system. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience and peptide-based drug discovery.

Application

• Neuroscience Research: Used as a high-purity reference standard and tool compound for studying endogenous opioid pathways, receptor binding assays, and signal transduction mechanisms.
• Analytical Standard: Serves as a critical calibrant and control in quantitative analytical methods such as HPLC and LC-MS for the detection and measurement of endorphins in biological matrices.
• Drug Discovery & Development: Acts as a key intermediate or lead compound in the design and synthesis of novel analgesics and neuropharmaceuticals with improved efficacy and reduced side-effect profiles.
• Biochemical Assays: Employed in vitro to investigate the physiological effects of β-endorphin analogs on cell cultures and tissue samples.
• Peptide Chemistry Studies: Utilized as a model compound for studying structure-activity relationships (SAR), peptide stability, and modification techniques.

Basic Information

Product Name	β-Endorphin, Cys(11,26),Phe(27), Gly(31)- CAS NO 96407-33-9
CAS No.	96407-33-9
Molecular Formula	C158H251N41O46S2
Molecular Weight	3466.1 g/mol (theoretical)
Synonyms	β-Endorphin (Cys11,26, Phe27, Gly31); [Cys11,26, Phe27, Gly31]-β-Endorphin; Modified β-Endorphin; β-Endorphin analog; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Cys-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Cys-Tyr-Gly-Gly-Phe-Leu-OH (disulfide bridge: Cys11-Cys26); Opioid peptide analog; LPH-(61-91), human (Cys11,26, Phe27, Gly31)
EINECS	Contact for details

Quality Control

Our β-Endorphin, Cys(11,26),Phe(27), Gly(31)- CAS NO 96407-33-9 is manufactured under controlled conditions to ensure the highest standards of purity and consistency. Each batch undergoes rigorous analytical testing, including HPLC for purity determination, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Amino Acid Composition	Conforms to theoretical values (±10%)
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.