Description

H-Thr-Gln-Oh CAS NO 96337-79-0 is a high-purity, protected dipeptide building block consisting of L-Threonine and L-Glutamine. This compound is essential for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Research & Development: Used in academic and industrial R&D for constructing custom peptide sequences to study structure-activity relationships (SAR).
• Bioconjugation: Acts as a spacer or linker molecule in the conjugation of peptides to other biomolecules, dyes, or solid supports.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Biochemical Reagents: Utilized as a substrate or standard in enzymatic assays and metabolic studies.
• Cosmetic Peptides: A potential raw material for the synthesis of bioactive peptides used in advanced skincare formulations.

Basic Information

Product Name	H-Thr-Gln-Oh
CAS No.	96337-79-0
Molecular Formula	C10H19N3O6
Molecular Weight	277.28 g/mol
Synonyms	H-Thr-Gln-OH; L-Threonyl-L-glutamine; Thr-Gln; TQ; H-L-Thr-L-Gln-OH; N-(tert-Butoxycarbonyl)-L-threonyl-L-glutamine; Boc-Thr-Gln-OH (related protected form); Fmoc-Thr-Gln-OH (related protected form); (2S,3R)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]-3-hydroxybutanoic acid
EINECS	Contact for details

Quality Control

Our H-Thr-Gln-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent screening. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines, where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.