Description

Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln is a high-purity synthetic peptide sequence, also known by its CAS number 96249-43-3. This compound is a critical intermediate and research tool in the development of novel therapeutic agents and diagnostic assays. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on protease activity, signal transduction pathways, and targeted drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key substrate or inhibitor in the study of specific proteolytic enzymes, particularly caspases involved in apoptosis.
• Biochemical Assay Development: Used as a standard or active component in the formulation of high-sensitivity diagnostic kits and enzymatic activity tests.
• Drug Discovery Platforms: Acts as a building block or a target-specific ligand in the screening and design of new therapeutic candidates.
• Academic & Clinical Research: Employed in fundamental studies of cellular mechanisms, disease pathology, and biomarker validation.
• Peptide Synthesis: Functions as an intermediate for the custom synthesis of longer, more complex peptide chains for specialized applications.

Basic Information

Product Name	Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln
CAS No.	96249-43-3
Molecular Formula	C58H86N12O21
Molecular Weight	1263.4 g/mol
Synonyms	AVVADADEYLIPQ; Caspase-3 Substrate (Ac-DEVD-AMC related sequence); Aspartyl-valyl-valyl-aspartyl-alanyl-aspartyl-glutamyl-tyrosyl-leucyl-isoleucyl-prolyl-glutamine; DEVDase Substrate Peptide; Ac-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln; Apoptosis-related Peptide; ICE/CED-3 Protease Substrate Analog
EINECS	Contact for details

Quality Control

Every batch of Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA), providing specifications for identity, purity (by HPLC), and peptide content, is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.