Description

Atrial Natriuretic Factor (7-23) is a synthetic peptide fragment corresponding to residues 7-23 of the human atrial natriuretic peptide (ANP) hormone. This bioactive sequence is critical for research into cardiovascular physiology and renal function, serving as a key tool for studying natriuresis, diuresis, and vasodilation mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on cardiorenal therapeutics and diagnostic assay development.

Application

• Biomedical Research: Fundamental studies on the structure-activity relationship (SAR) of atrial natriuretic peptide and its receptor binding.
• Pharmacological Assays: Used as a reference standard or competitive ligand in receptor binding assays and bioactivity tests.
• Antibody Production: Acts as an immunogen for generating specific antibodies used in immunoassays (ELISA, RIA) and immunohistochemistry.
• Drug Discovery: Screening and evaluation of novel compounds targeting the natriuretic peptide pathway for heart failure and hypertension.
• Diagnostic Development: Component in the calibration and validation of clinical diagnostic kits measuring ANP-related biomarkers.
• Biochemical Tool: Investigation of signal transduction pathways involving cyclic GMP (cGMP) as a second messenger.

Basic Information

Product Name	Atrial Natriuretic Factor (7-23)
CAS No.	96235-91-5
Molecular Formula	C78H122N24O23S2
Molecular Weight	1836.1 g/mol
Synonyms	ANF (7-23); Atrial Natriuretic Peptide (7-23); ANP (7-23); hANP (7-23); Cardionatrin (7-23); Atriopeptin (7-23); Auriculin A (7-23); Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Factor (7-23) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, peptide content, and solvent residues.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.