Description

Cyclo[L-Ala-Gly-[(2S)-8-Oxo-2-Amino*-8-Oxiranyloctanoyl]-D-Pro-] is a specialized cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 96090-02-7, is valued for its unique structural framework, which incorporates an oxirane (epoxide) functional group, making it a key intermediate or building block for probing biological activity and designing novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of peptide-based drugs, enzyme inhibitors, and targeted molecular probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in biochemical research to study and develop inhibitors for specific proteolytic enzymes due to its cyclic peptide structure.
• Chemical Biology Probe: Employed as a molecular tool to investigate protein-protein interactions and cellular signaling pathways.
• Medicinal Chemistry: Acts as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• Bioconjugation: The reactive epoxide moiety can be utilized for site-specific conjugation with biomolecules like proteins or antibodies.
• Academic & Industrial R&D: Fundamental research in organic synthesis, peptide chemistry, and the development of new therapeutic modalities.

Basic Information

Product Name	Cyclo[L-Ala-Gly-[(2S)-8-Oxo-2-Amino*-8-Oxiranyloctanoyl]-D-Pro-]
CAS No.	96090-02-7
Molecular Formula	C18H26N4O6
Molecular Weight	394.42 g/mol
Synonyms	Cyclo(L-alanyl-glycyl-[(2S)-8-oxo-2-amino-8-oxiranyloctanoyl]-D-prolyl); Cyclo(L-Ala-Gly-[(2S)-8-Oxo-2-Amino-8-Oxiranyloctanoyl]-D-Pro); Cyclo[L-Ala-Gly-[(2S)-8-Oxo-2-Amino-8-Oxiranyloctanoyl]-D-Pro-]; Epoxide-containing cyclic peptide derivative; Cyclo(Ala-Gly-epoxyketone-Pro); 96090-02-7; Epoxyketone cyclic dipeptide analog
EINECS	Contact for details

Quality Control

Our Cyclo[L-Ala-Gly-[(2S)-8-Oxo-2-Amino*-8-Oxiranyloctanoyl]-D-Pro-] is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.