Description

S-(2-Nitrocarbobenzoxy)Glutathione is a specialized, chemically modified derivative of the essential tripeptide glutathione, designed for advanced biochemical research and synthesis. This compound matters as a critical reagent and building block for studying enzyme mechanisms, particularly those involving glutathione S-transferases, and for the development of novel prodrugs and targeted therapeutic agents. It is primarily needed by pharmaceutical R&D teams, biochemical researchers, and fine chemical manufacturers focused on redox biology, drug discovery, and proteomics.

Application

• Biochemical Research: A key substrate and inhibitor for investigating the activity and kinetics of glutathione S-transferase (GST) enzymes.
• Pharmaceutical Development: Serves as a versatile intermediate in the synthesis of prodrugs and targeted molecules designed to exploit cellular glutathione pathways.
• Proteomics & Labeling: Used as a chemical probe for protein labeling and affinity purification studies due to its reactive S-(2-nitrocarbobenzoxy) protecting group.
• Antioxidant Mechanism Studies: Employed in research models to study the modulation of cellular redox states and oxidative stress responses.
• Reference Standard: Utilized as a high-purity analytical standard for quality control in the production of related peptide derivatives and research chemicals.

Basic Information

Product Name	S-(2-Nitrocarbobenzoxy)Glutathione
CAS No.	95998-73-5
Molecular Formula	C20H27N5O10S
Molecular Weight	529.52 g/mol
Synonyms	S-(2-Nitrobenzyloxycarbonyl)glutathione; Glutathione S-(2-nitrobenzyl) carbonate; NSC 401005; γ-Glu-Cys-Gly S-(2-nitrobenzyloxycarbonyl); S-(2-Nitrobenzyl) glutathione thiocarbonate; 2-Nitrobenzyloxycarbonyl-glutathione; S-(2-NCBz)-Glutathione; L-γ-Glutamyl-L-cysteinylglycine S-(2-nitrobenzyl) ester
EINECS	Contact for details

Quality Control

Every batch of S-(2-Nitrocarbobenzoxy)Glutathione is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.