Description

H-Val-Leu-Oh Hcl is a protected dipeptide building block, specifically the hydrochloride salt of H-Val-Leu-OH. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, development of bioactive peptides, and proteomics research.

Application

• Pharmaceutical Intermediate: A key building block for the solid-phase and solution-phase synthesis of therapeutic peptides targeting various diseases.
• Biochemical Research: Used in proteomics and enzymology studies to investigate peptide-protein interactions and enzyme specificity.
• Drug Discovery: Serves as a core scaffold or fragment in the design and development of novel peptidomimetic drug candidates.
• Custom Peptide Synthesis: An essential raw material for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) producing custom peptides for clients.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in peptide manufacturing.

Basic Information

Product Name	H-Val-Leu-Oh Hcl
CAS No.	95977-55-2
Molecular Formula	C11H23ClN2O3
Molecular Weight	266.77 g/mol
Synonyms	L-Valyl-L-leucine hydrochloride; Val-Leu-OH•HCl; H-Val-Leu-OH hydrochloride; N-(tert-Butoxycarbonyl)-L-valyl-L-leucine hydrochloride (common protected form precursor); BoC-Val-Leu-OH•HCl; V-L dipeptide HCl; L-Val-L-Leu dipeptide hydrochloride salt; 2-[(2-Amino-3-methylbutanoyl)amino]-4-methylpentanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our H-Val-Leu-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via mass spectrometry and IR spectroscopy. Certificates of Analysis (COA) with detailed specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.