Description

5-Iodo-2-(Piperazin-1-Yl)Pyrimidine is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry programs targeting kinase inhibition and other therapeutic modalities. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules and chemical libraries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially for oncology and CNS-related targets.
• Kinase Inhibitor Development: Used to construct core scaffolds for novel protein kinase inhibitors due to the pyrimidine-piperazine pharmacophore.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds or affinity probes for target identification and validation studies.
• Agrochemical Research: Employed in the discovery and development of new active ingredients for crop protection.
• Material Science: Potential monomer or precursor for creating specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name	5-Iodo-2-(Piperazin-1-Yl)Pyrimidine
CAS No.	95847-41-9
Molecular Formula	C8H11IN4
Molecular Weight	290.11 g/mol
Synonyms	2-(Piperazin-1-yl)-5-iodopyrimidine; 5-Iodo-2-piperazin-1-ylpyrimidine; 5-Iodo-2-(1-piperazinyl)pyrimidine; 95847-41-9; 5-Iodo-2-piperazinopyrimidine; Pyrimidine, 5-iodo-2-(1-piperazinyl)-; 2-(Piperazin-1-Yl)-5-Iodopyrimidine
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-(Piperazin-1-Yl)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.