Description

2-Chloro-6-(Morpholin-4-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, particularly in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of targeted small-molecule drugs. Its unique purine-based structure, functionalized with chloro and morpholino groups, makes it a versatile precursor for further chemical modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of adenosine receptor antagonists and other purine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Nucleoside/Nucleotide Analog Synthesis: Serves as a protected purine scaffold for creating modified nucleosides with potential antiviral or anticancer activity.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition, particularly kinases and other purine-binding proteins.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	2-Chloro-6-(Morpholin-4-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine
CAS No.	95758-04-6
Molecular Formula	C14H18ClN5O2
Molecular Weight	323.78 g/mol
Synonyms	2-Chloro-6-morpholino-9-(tetrahydro-2H-pyran-2-yl)-9H-purine; 9-(Tetrahydro-2H-pyran-2-yl)-2-chloro-6-(4-morpholinyl)-9H-purine; 2-Chloro-6-morpholino-9H-purine THP-protected; 95758-04-6; Purine, 2-chloro-6-(4-morpholinyl)-9-(tetrahydro-2H-pyran-2-yl)-; THP-protected 2-chloro-6-morpholinopurine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Morpholin-4-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.