Description

Z-Gln-Obzl is a protected glutamine derivative, specifically the benzyl ester of N-carbobenzoxy-L-glutamine, with the CAS registry number 95700-16-6. This compound serves as a crucial building block in peptide synthesis, offering precise control over the glutamine residue while preventing unwanted side reactions. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers involved in developing therapeutic peptides, bioactive compounds, and advanced materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid for the controlled incorporation of glutamine into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for research-scale and custom peptide production.
• Pharmaceutical Intermediate: A critical precursor in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Employed in the chemical modification of proteins or other biomolecules to introduce glutamine functionalities.
• Biochemical Research: Used as a substrate or intermediate in enzymatic studies and metabolic pathway investigations.
• Material Science: A monomer for creating specialized polyamino acids or peptide-polymer hybrids with specific properties.

Basic Information

Product Name	Z-Gln-Obzl
CAS No.	95700-16-6
Molecular Formula	C₂₀H₂₂N₂O₆
Molecular Weight	386.40 g/mol
Synonyms	N-Carbobenzoxy-L-glutamine benzyl ester; Z-L-Glutamine benzyl ester; Z-Gln-OBzl; Nα-Cbz-L-glutamine benzyl ester; Benzyl N-(benzyloxycarbonyl)-L-glutaminate; (S)-Benzyl 2-((benzyloxycarbonyl)amino)-5-oxo-5-(benzyloxy)pentanoate; Cbz-Gln-OBzl; Z-Glutamine-OBzl
EINECS	Contact for details

Quality Control

Our Z-Gln-Obzl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the stringent requirements for peptide synthesis intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.