Description

Cholecystokinin 22 C-Terminal Fragment CAS NO 95690-77-0 is a bioactive peptide fragment derived from the gastrointestinal hormone cholecystokinin (CCK). This compound is of significant value in biochemical and pharmacological research due to its role in studying receptor binding, signal transduction, and digestive system functions. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on neurogastroenterology and metabolic studies.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying cholecystokinin receptor (CCK1 and CCK2) interactions and signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or active pharmacophore in the discovery and development of drugs targeting gastrointestinal disorders, appetite regulation, and anxiety.
• Diagnostic Assays: Employed in the development and calibration of immunoassays (ELISA, RIA) to measure CCK levels in biological samples for clinical research.
• Neuroscience Studies: Utilized to investigate the role of CCK in the brain-gut axis, including its effects on satiety, pain perception, and behavior.
• Academic & Contract Research: A critical reagent for in vitro and ex vivo studies in university labs and CROs (Contract Research Organizations) specializing in endocrinology.

Basic Information

Product Name	Cholecystokinin 22 C-Terminal Fragment
CAS No.	95690-77-0
Molecular Formula	C129H204N36O39S
Molecular Weight	2859.3 g/mol
Synonyms	CCK-22 C-Terminal Fragment; Cholecystokinin (30-52), human; CCK (30-52); Sincalide fragment; CCK-22; H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (sulfated form); CCK octapeptide analog; Pancreozymin fragment.
EINECS	Contact for details

Quality Control

Our Cholecystokinin 22 C-Terminal Fragment is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and residual moisture is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the peptide desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.