Description

Glycyl-Prolyl-Methionyl-2-Naphthylamide is a synthetic tripeptide derivative designed as a specialized chromogenic substrate for enzymatic assays. This compound is of significant value in biochemical research and pharmaceutical development for its role in the specific detection and quantification of protease activity. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in enzyme kinetics studies and high-throughput screening.

Application

• Protease Activity Assays: Serves as a specific chromogenic substrate for the detection and kinetic analysis of various proteolytic enzymes, including dipeptidyl peptidases and aminopeptidases.
• Biochemical Research: Used in fundamental research to study enzyme mechanisms, inhibition, and substrate specificity in purified enzyme systems.
• Diagnostic Development: Employed in the formulation of diagnostic kits for clinical and research laboratories to measure specific enzyme levels in biological samples.
• Pharmaceutical Screening: Utilized in high-throughput screening (HTS) platforms to identify and characterize potential protease inhibitors as novel therapeutic agents.
• Quality Control in Biomanufacturing: Applied in monitoring the activity and consistency of enzyme preparations used in biotechnological processes.

Basic Information

Product Name	Glycyl-Prolyl-Methionyl-2-Naphthylamide
CAS No.	95574-36-0
Molecular Formula	C25H33N5O4S
Molecular Weight	499.63 g/mol
Synonyms	Gly-Pro-Met-2NA; GPM-2NA; GP-Met-2-Naphthylamide; L-Glycyl-L-prolyl-L-methionine 2-naphthylamide; Substrate for DPP IV; Dipeptidyl Peptidase IV Substrate; Chromogenic Peptide Substrate; 2-Naphthylamide-Gly-Pro-Met
EINECS	Contact for details

Quality Control

Our Glycyl-Prolyl-Methionyl-2-Naphthylamide is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay systems. We adhere to relevant quality management standards to guarantee reliable supply and product integrity for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Solubility	Clear, colorless solution in DMSO or DMF
Functional Activity	Conforms to reference in standard assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.