Description

Tyrosyl-Alanyl-Glycyl-(4-Azidomethylphenylalanyl)-Glycine-Oh is a specialized synthetic peptide containing a photoreactive azidomethylphenylalanine residue. This compound matters as a critical biochemical tool for photoaffinity labeling and cross-linking studies, enabling researchers to probe protein-protein interactions and ligand binding sites with high precision. It is primarily needed by pharmaceutical R&D teams, academic biochemistry laboratories, and bioconjugation specialists developing targeted therapies and diagnostic agents.

Application

• Photoaffinity Labeling Probe: Used to covalently tag and identify biological targets, such as receptors and enzymes, upon UV light activation.
• Bioconjugation & Cross-linking: Serves as a key intermediate for site-specific conjugation of peptides to other biomolecules, antibodies, or solid surfaces.
• Structural Biology Studies: Employed in mapping protein interaction interfaces and active sites through irreversible cross-linking.
• Drug Discovery Research: Integral to the development of novel peptide-based therapeutics and targeted drug delivery systems.
• Proteomics & Chemical Biology: A valuable reagent for activity-based protein profiling (ABPP) and understanding complex cellular pathways.
• Material Science Functionalization: Used to introduce bioactive peptide motifs onto polymers or nanomaterials for advanced biomaterial development.

Basic Information

Product Name	Tyrosyl-Alanyl-Glycyl-(4-Azidomethylphenylalanyl)-Glycine-Oh
CAS No.	95537-14-7
Molecular Formula	C31H39N9O8
Molecular Weight	665.70 g/mol
Synonyms	Y-A-G-(F4N3)-G-OH; Tyr-Ala-Gly-(4-Azidomethyl-Phe)-Gly-OH; TFA Salt of YAGF(N3)G; Photoaffinity Labeling Peptide YAG(F4N3)G; H-Tyr-Ala-Gly-Phe(4-CH2N3)-Gly-OH; Azidomethylphenylalanine-containing Pentapeptide; CAS 95537-14-7; Azido Photoprobe Peptide
EINECS	Contact for details

Quality Control

Our Tyrosyl-Alanyl-Glycyl-(4-Azidomethylphenylalanyl)-Glycine-Oh is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development. Certificates of Analysis (COA) with detailed HPLC, MS, and NMR data are provided to guarantee traceability and compliance with your specific research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.