Description

Somatotropin Releasing Hormone (1-24)Amide is a bioactive synthetic peptide fragment of growth hormone-releasing hormone (GHRH). This compound is critical for research and development in endocrinology and metabolic studies due to its specific stimulatory effect on somatotropin (growth hormone) secretion. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing diagnostic tools and therapeutic agents for growth-related disorders.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of growth hormone secretagogues and diagnostic agents.
• Endocrinology Studies: Used in in vitro and in vivo research to investigate the hypothalamic-pituitary axis, growth hormone regulation, and related metabolic pathways.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) and receptor binding assays for growth hormone-releasing hormone activity.
• Veterinary Science Applications: Investigated for potential applications in animal growth promotion and metabolic research within agricultural biotechnology.
• Peptide Chemistry & Synthesis: Used as a building block or reference compound in advanced peptide synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Somatotropin Releasing Hormone (1-24)Amide
CAS No.	95415-63-7
Molecular Formula	C₁₁₀H₁₇₈N₄₄O₃₃
Molecular Weight	~2859.2 g/mol
Synonyms	GHRH (1-24) amide; Growth Hormone-Releasing Factor (1-24) amide; Somatoliberin (1-24) amide; GRF (1-24) amide; hpGRF (1-24) amide; Human Pancreatic Growth Hormone-Releasing Factor (1-24) amide; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-NH₂; Sermorelin Acetate (related acetate salt form)
EINECS	Contact for details

Quality Control

Our Somatotropin Releasing Hormone (1-24)Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and biological activity, meeting the stringent requirements for research-grade peptides. Certificates of Analysis (COA) detailing HPLC purity, amino acid analysis, mass spectrometry (MS) data, and endotoxin levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak consistent with theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Analysis	± 10% of theoretical composition
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0% (if applicable)
Biological Activity	Stimulates GH release in a cell-based assay (Data available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.