Description

1-(4-Chlorophenyl)-2-Cyclobutylquinazolin-4(1H)-One is a specialized quinazolinone derivative, a high-value chemical intermediate prized for its unique molecular scaffold. This compound matters for its role in advanced pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study biological pathways and enzyme functions.
• Material Science Precursor: Potential intermediate in the synthesis of advanced organic materials and ligands for catalysis.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(4-Chlorophenyl)-2-Cyclobutylquinazolin-4(1H)-One
CAS No.	95216-42-5
Molecular Formula	C₁₈H₁₅ClN₂O
Molecular Weight	310.78 g/mol
Synonyms	1-(4-Chlorophenyl)-2-cyclobutyl-1,4-dihydroquinazolin-4-one; 2-Cyclobutyl-1-(4-chlorophenyl)quinazolin-4(1H)-one; 4(1H)-Quinazolinone, 1-(4-chlorophenyl)-2-cyclobutyl-; Quinazolin-4(1H)-one, 1-(4-chlorophenyl)-2-cyclobutyl-; 95216-42-5; 1-(p-Chlorophenyl)-2-cyclobutylquinazolin-4(1H)-one
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-2-Cyclobutylquinazolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.