Description

Beta Casomorphin 8, Human CAS NO 95210-75-6 is a bioactive opioid peptide derived from the enzymatic digestion of human β-casein. This compound is of significant interest in biochemical and pharmacological research due to its role as a selective mu-opioid receptor agonist. It serves as a critical reference standard and research tool for scientists investigating neurobiology, gastrointestinal physiology, and the physiological effects of dietary peptides. Target users include pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on peptide science and opioid pathway studies.

Application

• Pharmacological Research: Used as a reference standard in studies of mu-opioid receptor binding, activation, and signal transduction pathways.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) and receptor-binding assays.
• Neuroscience Studies: Employed to investigate the effects of exogenous opioid peptides on pain perception, behavior, and central nervous system function.
• Gastrointestinal Physiology Research: Applied in studies examining the impact of casomorphins on gut motility, permeability, and the gut-brain axis.
• Analytical Reference Standard: Essential for the qualitative and quantitative analysis (e.g., via HPLC, LC-MS) of casomorphins in complex biological matrices or food products.
• Drug Discovery & Development: Acts as a lead compound or tool for screening and evaluating novel opioid modulators and analgesics.

Basic Information

Item	Detail
Product Name	Beta Casomorphin 8, Human
CAS No.	95210-75-6
Molecular Formula	C₄₁H₅₆N₁₀O₁₂
Molecular Weight	881.0 g/mol
Synonyms	β-Casomorphin-8; Human β-Casomorphin 8; β-CM-8; Tyr-Pro-Phe-Val-Glu-Pro-Ile-Pro; YPFVEPIP; β-Casomorphin (1-8); Opioid peptide β-casomorphin-8; H-Tyr-Pro-Phe-Val-Glu-Pro-Ile-Pro-OH
EINECS	Contact for details

Quality Control

Our Beta Casomorphin 8, Human is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Standard quality control includes HPLC purity analysis, mass spectrometry (MS) for confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting research reproducibility and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80% (by amino acid analysis)
Solubility	Soluble in water, dimethyl sulfoxide (DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.