Description

Suc-Ala-Val-Pro-Phe-Pna CAS NO 95192-38-4 is a synthetic peptide substrate designed for enzymatic activity studies. This compound is of significant value in biochemical and pharmaceutical research for its role in investigating protease specificity and kinetics. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in drug discovery and enzyme mechanism analysis.

Application

• Protease Substrate: Used as a specific chromogenic substrate for the study of chymotrypsin, elastase, and related serine proteases.
• Biochemical Research: Essential for kinetic assays, enzyme inhibition studies, and determining protease activity in complex biological samples.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) campaigns to identify and characterize novel protease inhibitors as potential drug candidates.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of diagnostic kits for measuring protease levels relevant to certain disease states.
• Enzyme Characterization: Aids in defining the cleavage specificity and catalytic efficiency of newly discovered or engineered proteases.

Basic Information

Product Name	Suc-Ala-Val-Pro-Phe-Pna
CAS No.	95192-38-4
Molecular Formula	C34H44N6O9
Molecular Weight	680.75 g/mol
Synonyms	N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide; Suc-AAPF-pNA; Suc-Ala-Ala-Pro-Phe-pNA; N-Succinyl-Alanyl-Alanyl-Prolyl-Phenylalanine 4-Nitroanilide; Substrate for Chymotrypsin; Protease Substrate IV; AAPF-pNA; Suc-AAPF-pNA Substrate
EINECS	Contact for details

Quality Control

Our Suc-Ala-Val-Pro-Phe-Pna is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by mass spectrometry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to ensure compliance with your research and manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.