Description

3-(1-β-D-Arabinofuranosyl-1,2,3,4-Tetrahydro-2,4-Dioxopyrimidin-5-Yl)Acrylic Acid is a high-purity nucleoside derivative and a key synthetic intermediate in advanced pharmaceutical research. This compound is valued for its role in the development of novel antiviral and anticancer therapeutics, particularly as a precursor for modified nucleoside analogs. It is essential for research and development laboratories, pharmaceutical manufacturers, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic candidates targeting viral polymerases and other enzymes.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to understand nucleotide metabolism and related pathways.
• Preclinical Development: Employed in the production of active pharmaceutical ingredients (APIs) for early-stage clinical trials.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	3-(1-β-D-Arabinofuranosyl-1,2,3,4-Tetrahydro-2,4-Dioxopyrimidin-5-Yl)Acrylic Acid
CAS No.	95119-95-2
Molecular Formula	C12H14N2O8
Molecular Weight	314.25 g/mol
Synonyms	5-(2-Carboxyvinyl)-1-(β-D-arabinofuranosyl)dihydrouracil; 1-(β-D-Arabinofuranosyl)-5-(2-carboxyethenyl)dihydrouracil; 5-(2-Carboxyethenyl)-1-(β-D-arabinofuranosyl)-1,2,3,4-tetrahydro-2,4-pyrimidinedione; 5-(2-Carboxyvinyl)-1-(β-D-arabinofuranosyl)-1,2,3,4-tetrahydro-2,4-pyrimidinedione; 3-(1-β-D-Arabinofuranosyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl)prop-2-enoic acid; Dihydrouracil arabinoside acrylic acid derivative
EINECS	Contact for details

Quality Control

Our 3-(1-β-D-Arabinofuranosyl-1,2,3,4-Tetrahydro-2,4-Dioxopyrimidin-5-Yl)Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.