Description

D-Glucosyl--1,1' n-Stearoyl-D-Erythro-Sphingosine is a high-purity synthetic glycosphingolipid, specifically a glucosylceramide derivative. This compound serves as a critical reference standard and building block in advanced lipidomics research and the development of novel therapeutic agents. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries who require well-defined, structurally complex lipids for analytical, diagnostic, and formulation purposes.

Application

• Biomedical Research Standard: Used as a certified reference material (CRM) for the quantification and identification of glycosphingolipids in mass spectrometry and chromatography.
• Drug Discovery & Development: Acts as a key intermediate or target molecule in the synthesis of novel drugs targeting metabolic disorders like Gaucher's disease.
• Cell Biology Studies: Employed in research on cell membrane structure, lipid rafts, and cell signaling pathways to understand their role in health and disease.
• Cosmetic Science: Investigated for its potential skin barrier repair and moisturizing properties in high-end skincare formulations.
• Diagnostic Reagent Manufacturing: Utilized in the production of calibrators and controls for clinical diagnostic kits targeting sphingolipidoses.
• Enzyme Substrate: Serves as a specific substrate for enzyme activity assays, particularly for glucocerebrosidase and other related hydrolases.

Basic Information

Product Name	D-Glucosyl--1,1' n-Stearoyl-D-Erythro-Sphingosine
CAS No.	95119-86-1
Molecular Formula	C42H81NO9
Molecular Weight	744.10 g/mol
Synonyms	Glucosylceramide (C18:0); β-D-Glucosyl-N-octadecanoylsphingosine; N-Stearoyl-D-glucosylsphingosine; D-Glucosylceramide (d18:1/18:0); N-(1-((2S,3R,4E)-3-Hydroxy-1-(β-D-glucopyranosyloxy)-4-octadecen-2-yl)octadecanamide); Gaucher's disease biomarker; GlcCer(18:1/18:0); Glucosyl-β1-1'-N-stearoylsphingosine
EINECS	Contact for details

Quality Control

Every batch of D-Glucosyl--1,1' n-Stearoyl-D-Erythro-Sphingosine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.