Description

2,3-Diamino-6-(trifluoromethyl)-4(3H)-pyrimidinone is a high-value, multi-functional heterocyclic building block characterized by its reactive diamine and carbonyl groups on a fluorinated pyrimidinone scaffold. This compound matters for its critical role in the synthesis of advanced pharmaceutical intermediates and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral, anticancer, and central nervous system (CNS) active drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides leveraging the bioactivity of the pyrimidinone core.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology & Proteomics: Serves as a scaffold for designing enzyme inhibitors, probes, and molecular tags in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library generation.

Basic Information

Product Name	2,3-Diamino-6-(trifluoromethyl)-4(3H)-pyrimidinone
CAS No.	95095-71-9
Molecular Formula	C5H5F3N4O
Molecular Weight	194.12 g/mol
Synonyms	6-(Trifluoromethyl)-2,3-diamino-4(3H)-pyrimidinone; 2,3-Diamino-6-trifluoromethyl-4-pyrimidinol; 4(3H)-Pyrimidinone, 2,3-diamino-6-(trifluoromethyl)-; 2,3-Diamino-6-(trifluoromethyl)pyrimidin-4(3H)-one; 95095-71-9; 6-Trifluoromethyl-2,3-diamino-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 2,3-Diamino-6-(trifluoromethyl)-4(3H)-pyrimidinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.