Description

Angiotensin II Acetate is a synthetic peptide analog of the endogenous vasoconstrictor hormone, Angiotensin II, with the acetate salt form enhancing its stability for research and development use. This compound is a critical tool for studying the renin-angiotensin system (RAS), which regulates blood pressure, fluid balance, and cardiovascular function. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and academic institutions engaged in cardiovascular, renal, and metabolic disease research.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating hypertension, heart failure, and kidney disease pathways.
• Drug Discovery & Development: Serves as a key ligand for screening and validating potential Angiotensin II receptor antagonists and ACE inhibitors.
• Biochemical Assays: Employed in receptor binding studies, cell-based functional assays, and signal transduction research to elucidate RAS mechanisms.
• In Vitro Diagnostics (IVD): Can be used in the development of calibration standards for diagnostic kits targeting components of the renin-angiotensin system.
• Academic & Preclinical Studies: Essential for fundamental research in physiology and pharmacology within university and institutional labs.

Basic Information

Product Name	Angiotensin II Acetate
CAS No.	94881-02-4
Molecular Formula	C50H71N13O12 • (C2H4O2)x
Molecular Weight	1046.2 g/mol (free base)
Synonyms	Angiotensin II; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe; DRVYIHPF; All-Des-Asp1-Angiotensin I; Angiotensin II Human; [Asn1, Val5]-Angiotensin II; Hypertensin; Angiotensin Amide
EINECS	Contact for details

Quality Control

Our Angiotensin II Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis to meet specific purity or packaging requirements is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	Reported on COA
Peptide Content	≥ 80%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.