Description

D-Ala-Gly-Phe-D-Leu Acetate Salt is a synthetic peptide derivative, specifically a tetrapeptide with a D-amino acid configuration, which is crucial for its stability against enzymatic degradation. This compound is primarily valued as a key intermediate in advanced pharmaceutical research and development, particularly in the synthesis of novel peptide-based therapeutics and diagnostic agents. It serves the needs of research institutions, pharmaceutical companies, and biotechnology firms focused on neurobiology, metabolic studies, and the development of receptor-targeted drugs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex peptide drugs and hormone analogs.
• Biomedical Research: Used as a reference standard or active component in studies of enzyme inhibition, receptor binding assays, and signal transduction pathways.
• Peptide Library Synthesis: A valuable component in combinatorial chemistry for creating diverse peptide libraries to screen for biological activity.
• Neuroscience Research: Potential application in the study of opioid receptors and related neurological functions due to its peptide sequence.
• Diagnostic Agent Development: Can be utilized in the development of labeled peptides for imaging and diagnostic purposes.

Basic Information

Product Name	D-Ala-Gly-Phe-D-Leu Acetate Salt
CAS No.	94825-17-9
Molecular Formula	C22H32N4O6 • xC2H4O2
Molecular Weight	472.52 g/mol (Free base)
Synonyms	D-Alanine-Glycine-Phenylalanine-D-Leucine Acetate; H-D-Ala-Gly-Phe-D-Leu-OH Acetate; Tetrapeptide DAGFDLA; DAGFDL Acetate; (2R)-2-[[(2S)-2-[[2-[[(2R)-2-Amino-1-oxopropyl]amino]acetyl]amino]-3-phenyl-1-oxopropyl]amino]-4-methyl-1-oxopentyl]ammonium acetate; D-Ala-Gly-Phe-D-Leu-OH • AcOH; DAGFDL-OH Acetate Salt
EINECS	Contact for details

Quality Control

Our D-Ala-Gly-Phe-D-Leu Acetate Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure the correct stereochemistry. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥98.0%
Chiral Purity	≥99.0%
Water Content (KF)	≤5.0%
Acetate Content (Titration)	1.0 - 2.0 eq
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.