Description

4-Amino-2-Chloropyrimidine-5-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its unique molecular structure, featuring both amino and nitrile substituents on a chlorinated pyrimidine core, makes it a versatile intermediate for synthesizing complex molecules. This compound is essential for pharmaceutical R&D, particularly in the development of kinase inhibitors and other active pharmaceutical ingredients (APIs), as well as for advanced agrochemicals and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in medicinal and synthetic chemistry.
• Material Science: Potential intermediate for the development of organic electronic materials and specialty polymers.
• Dye & Pigment Industry: Can be utilized in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	4-Amino-2-Chloropyrimidine-5-Carbonitrile
CAS No.	94741-69-2
Molecular Formula	C5H3ClN4
Molecular Weight	154.56 g/mol
Synonyms	2-Chloro-4-aminopyrimidine-5-carbonitrile; 5-Cyano-2-chloro-4-pyrimidinamine; 4-Amino-2-chloro-5-cyanopyrimidine; 2-Chloro-4-amino-5-cyanopyrimidine; 4-Pyrimidinamine, 2-chloro-5-cyano-; 94741-69-2; AC5C; 2-Chloro-4-aminopyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloropyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.