Description

H-Ala-Ala-4-Abz-Oh is a specialized dipeptide derivative containing the 4-aminobenzoic acid (4-Abz) moiety. This compound is a crucial building block and intermediate in advanced peptide synthesis and biochemical research. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in protease substrate development and medicinal chemistry.

Application

• Protease Substrate Development: Used as a key intermediate in the design and synthesis of fluorogenic and chromogenic substrates for studying enzyme kinetics and inhibitor screening.
• Medicinal Chemistry Research: Serves as a building block for creating novel peptide-based drug candidates and molecular probes targeting specific biological pathways.
• Biochemical Assays: Employed in the development of high-throughput screening assays to identify and characterize protease activity.
• Chemical Biology Tools: Integral for synthesizing activity-based probes (ABPs) used to profile enzyme function in complex biological systems.
• Custom Peptide Synthesis: A valuable starting material for contract research organizations (CROs) and manufacturers producing custom peptides for research and diagnostic applications.

Basic Information

Product Name	H-Ala-Ala-4-Abz-Oh
CAS No.	94722-22-2
Molecular Formula	C16H21N3O5
Molecular Weight	335.36 g/mol
Synonyms	H-Ala-Ala-4-Abz-OH; L-Alanyl-L-alanyl-4-aminobenzoic acid; N-(4-Aminobenzoyl)-L-alanyl-L-alanine; Ala-Ala-4-Abz; 4-Aminobenzoyl-Ala-Ala-OH; A-A-4-Abz; 94722-22-2; Peptide substrate intermediate A-A-4-Abz
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-4-Abz-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.