Description

Tyrosyl-Alanyl-Glycyl-Phenylalanyl-Cysteine S-Ethyl Ester is a synthetic pentapeptide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a crucial building block and model substrate for studying enzyme kinetics, peptide synthesis methodologies, and structure-activity relationships. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, drug discovery, and the development of novel therapeutic agents. The S-ethyl ester moiety provides specific reactivity and stability characteristics that are valuable for targeted chemical modifications.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and screening of novel peptide-based drug candidates.
• Biochemical Studies: Serves as a specific substrate for investigating the activity and inhibition of proteolytic enzymes like cysteine proteases.
• Proteomics & Peptide Chemistry: Acts as a model compound for developing and optimizing new peptide coupling, deprotection, and purification techniques.
• Academic Research: Employed in university and institutional labs for fundamental studies on peptide structure, folding, and biological function.
• Reference Standard: Utilized as a high-purity calibrant in analytical methods such as HPLC and mass spectrometry for quality control of related peptide products.

Basic Information

Product Name	Tyrosyl-Alanyl-Glycyl-Phenylalanyl-Cysteine S-Ethyl Ester
CAS No.	94492-33-8
Molecular Formula	C31H41N5O8S
Molecular Weight	643.75 g/mol
Synonyms	Tyr-Ala-Gly-Phe-Cys-S-Et; YAGFC(S-Et); H-Tyr-Ala-Gly-Phe-Cys-S-Et-OH; L-Tyrosyl-L-alanyl-glycyl-L-phenylalanyl-L-cysteine S-ethyl ester; Pentapeptide YAGFC(S-Et); S-Ethyl L-cysteinyl-L-tyrosyl-L-alanylglycyl-L-phenylalanine; N-[N-[N-[N-[N-(2-Amino-2-carboxyethylthio)carbonyl]-L-phenylalanyl]glycyl]-L-alanyl]-L-tyrosine ethyl ester
EINECS	Contact for details

Quality Control

Our Tyrosyl-Alanyl-Glycyl-Phenylalanyl-Cysteine S-Ethyl Ester is manufactured under controlled conditions to ensure the highest standards of purity and consistency. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, MS for identity confirmation, and chiral analysis to verify enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We are committed to meeting the stringent requirements of research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.