Description

Pelrinone CAS NO 94386-65-9 is a high-purity chemical compound belonging to the class of selective phosphodiesterase (PDE) inhibitors. This compound is valued for its specific biological activity, making it a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel cardiovascular and pulmonary therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced drug candidates targeting phosphodiesterase enzymes.
• Biochemical Research: Used as a reference standard and tool compound in enzymatic assays and pharmacological studies to investigate PDE inhibition mechanisms.
• Cardiovascular Research: Employed in preclinical research for developing potential treatments for heart failure and related conditions.
• Pulmonary Drug Discovery: Applied in research programs focused on discovering new therapies for asthma, chronic obstructive pulmonary disease (COPD), and pulmonary hypertension.
• Reference Material: Supplied as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.

Basic Information

Product Name	Pelrinone
CAS No.	94386-65-9
Molecular Formula	C16H14N2O3
Molecular Weight	282.30 g/mol
Synonyms	1,6-Dihydro-2-methyl-6-oxo-3,4'-bipyridine-5-carbonitrile; 3-Cyano-1,6-dihydro-2-methyl-6-oxo-3,4'-bipyridine; 4-(3-Cyano-1,6-dihydro-2-methyl-6-oxopyridin-3-yl)pyridine; Pelrinone (INN); 1,6-Dihydro-2-methyl-6-oxo-3-(4-pyridinyl)-5-pyridinecarbonitrile; 3-Cyano-1,6-dihydro-2-methyl-6-oxo-3-(4-pyridinyl)pyridine
EINECS	Contact for details

Quality Control

Our Pelrinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.