Description

Scillaren is a cardiac glycoside derived from plants of the *Scilla* genus, known for its potent biological activity. This high-purity compound is critical for pharmaceutical research and development, particularly in the study of cardiovascular pharmacology and drug discovery. It serves as a valuable reference standard and active pharmaceutical ingredient (API) intermediate for manufacturers and research institutions focused on cardiac therapeutics.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Cardiovascular Research: A key biochemical tool for in vitro and in vivo studies investigating cardiac muscle contractility, sodium-potassium ATPase inhibition, and heart failure mechanisms.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical starting material or intermediate in the synthesis of specialized cardiac medications.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays and diagnostic kits targeting cardiac biomarkers.
• Natural Product Isolation & Standardization: Used as a marker compound for the standardization and quality assessment of botanical extracts containing cardiac glycosides.
• Academic & Clinical Research: Supports fundamental research in pharmacology, toxicology, and physiology within university and hospital laboratories.

Basic Information

Product Name	Scillaren
CAS No.	11003-70-6
Molecular Formula	C36H52O13
Molecular Weight	692.80 g/mol
Synonyms	Scillaren A; Scillarenin 3-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranoside; Transvaalin; Urginea maritima glycoside A; Scillarain A; Scillarenin rhamnoglucoside; 6-[4,5-Dihydroxy-6-methyl-3-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]oxy]oxan-2-yl]oxy-4,5,14-trihydroxy-19-oxo-18,22-dioxapentacyclo[12.8.0.0²,¹¹.0⁵,¹⁰.0¹⁶,²¹]docosa-1(14),2(11),3,5(10),6,8,15,17,20-nonaen-13-yl acetate
EINECS	234-245-1

Quality Control

Our Scillaren is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant pharmacopeial standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.