Description

7-[3-(4-Phenethyl-1-Piperazinyl)-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione is a complex purine derivative with a piperazine side chain, representing a high-value pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular systems. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of proprietary APIs and investigational new drugs.
• Neurological Research: Used in the development of compounds targeting adenosine and dopamine receptor pathways.
• Cardiovascular Drug Development: Serves as a building block for potential vasodilators and anti-hypertensive agents.
• Chemical Biology & Proteomics: Utilized as a tool compound for studying enzyme inhibition and protein-ligand interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for commercial pharmaceutical manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	7-[3-(4-Phenethyl-1-Piperazinyl)-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione
CAS No.	19971-99-4
Molecular Formula	C22H30N6O3
Molecular Weight	426.52 g/mol
Synonyms	1,3-Dimethyl-7-[3-(4-phenethyl-1-piperazinyl)-2-hydroxypropyl]xanthine; 7-[3-(4-Phenethylpiperazin-1-yl)-2-hydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 1,3-Dimethyl-7-(3-(4-phenethyl-1-piperazinyl)-2-hydroxypropyl)xanthine; VUF 4779; VUF-4779; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-[3-(4-phenethyl-1-piperazinyl)-2-hydroxypropyl]-
EINECS	Contact for details

Quality Control

Our 7-[3-(4-Phenethyl-1-Piperazinyl)-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and cGMP starting materials. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), residual solvents, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.