Description

Bemarinone Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role in the development and synthesis of novel therapeutic agents, particularly in the field of cardiology. It is primarily required by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel inotropic agents for cardiovascular research.
• Biochemical Research: Used as a reference standard and active compound in pharmacological studies targeting cardiac muscle contractility.
• Drug Discovery & Development: Serves as a crucial starting material or precursor in medicinal chemistry programs for heart failure treatments.
• Analytical Standard: Employed for method development, calibration, and quality control in HPLC and LC-MS analysis within pharmaceutical labs.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Bemarinone Hydrochloride
CAS No.	101626-69-1
Molecular Formula	C19H17N3O3·HCl
Molecular Weight	371.82 g/mol
Synonyms	Bemarinone HCl; 1,3-Dihydro-5-[4-(3-methyl-1H-pyrazol-5-yl)phenyl]-2H-imidazo[4,5-b]pyridin-2-one hydrochloride; 5-[4-(3-Methyl-1H-pyrazol-5-yl)phenyl]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one hydrochloride; AR-L 115 BS; AR-L-115; ARL-115
EINECS	Contact for details

Quality Control

Our Bemarinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.