Description

Tuftsin-M is a synthetic peptide derivative of the natural immunomodulatory peptide Tuftsin, designed for enhanced stability and biological activity. This compound is a critical research tool and potential therapeutic agent for modulating the immune system. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions focused on immunology, oncology, and drug discovery.

Application

• Immunological Research: Used as a reference standard and active agent in studies of macrophage activation, phagocytosis, and cytokine modulation.
• Drug Discovery: Serves as a lead compound or building block for developing novel immunotherapies and anti-cancer agents.
• Biochemical Assays: Employed in in vitro and cell-based assays to study receptor-ligand interactions and signal transduction pathways.
• Peptide Chemistry: Acts as a substrate or intermediate for synthesizing more complex peptide conjugates and analogs.
• Preclinical Development: Investigated for potential applications in vaccine adjuvants and treatments for immune deficiencies or chronic infections.

Basic Information

Product Name	Tuftsin-M
CAS No.	94359-48-5
Molecular Formula	C27H44N8O7
Molecular Weight	568.69 g/mol
Synonyms	Thr-Lys-Pro-Arg-OH (TKPR); L-Threonyl-L-lysyl-L-prolyl-L-arginine; Tuftsin (Thr-Lys-Pro-Arg) acetate; Immunoglobulin-derived peptide TKPR; Tuftsin acetate salt; Arg-Pro-Lys-Thr; Tuftsin (human leukophilic γ-globulin) fragment; Tuftsin-M acetate
EINECS	Contact for details

Quality Control

Our Tuftsin-M is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent controls for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	Conforms
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.