Description

tert-Butyloxycarbonyl-Tryptophyl-Leucyl-Asparagine is a protected tripeptide building block of significant importance in synthetic organic and medicinal chemistry. Its core value lies in enabling the controlled, sequential synthesis of complex peptides and peptidomimetics, which are crucial for pharmaceutical research and development. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and academic sectors for the discovery and production of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the stepwise construction of longer peptide chains on resin supports.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for the preparation of specific peptide sequences in solution.
• Pharmaceutical Research: Serves as a critical building block in the discovery and development of peptide-based drugs, hormones, and enzyme inhibitors.
• Bioconjugation: Can be utilized to attach peptide epitopes or functional groups to other biomolecules, proteins, or surfaces.
• Structure-Activity Relationship (SAR) Studies: Employed to synthesize peptide analogs for biological testing to understand the relationship between chemical structure and therapeutic activity.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of specialized peptides for clients.

Basic Information

Product Name	tert-Butyloxycarbonyl-Tryptophyl-Leucyl-Asparagine
CAS No.	94236-41-6
Molecular Formula	C27H39N5O7
Molecular Weight	545.63 g/mol
Synonyms	Boc-Trp-Leu-Asn-OH; Boc-Tryptophyl-Leucyl-Asparagine; N-α-Boc-L-Tryptophyl-L-Leucyl-L-Asparagine; (2S)-2-[[(2S)-2-[[(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-carbamoylpropanoic Acid; Boc-L-Trp-L-Leu-L-Asn; Boc-Trp-Leu-Asparagine; tert-Butoxycarbonyl-Tryptophyl-Leucyl-Asparagine
EINECS	Contact for details

Quality Control

Our tert-Butyloxycarbonyl-Tryptophyl-Leucyl-Asparagine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We employ advanced analytical techniques including HPLC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.