Description

Human IL-2 is a high-purity, recombinant cytokine essential for regulating immune system responses, particularly T-cell proliferation and activation. Its critical role in immunology makes it a vital reagent for advanced biomedical research and therapeutic development. This product is indispensable for pharmaceutical R&D, biotechnology applications, and academic research focused on immunology, cancer therapy, and autoimmune diseases.

Application

• Immunotherapy Research: A key component in the study and development of adoptive cell therapies, including CAR-T and TIL therapies.
• T-Cell Culture & Expansion: Used in vitro to stimulate and maintain the growth of primary T-cells for experimental and clinical applications.
• Biologics & Vaccine Development: Serves as a critical reagent in the formulation and testing of novel vaccines and biologic drugs targeting the immune system.
• Diagnostic Assay Development: Employed as a standard or control in ELISA, flow cytometry, and other immunoassays to quantify immune responses.
• Autoimmune & Inflammatory Disease Studies: Used in research models to understand the pathophysiology of diseases like rheumatoid arthritis and lupus.
• Cell Signaling & Pathway Analysis: A tool for investigating the JAK-STAT signaling pathway and other downstream effects of interleukin activity.

Basic Information

Product Name	Human IL-2
CAS No.	94218-72-1
Molecular Formula	C690H1110N186O210S10
Molecular Weight	Approx. 15.5 kDa
Synonyms	Interleukin-2; IL-2; T-Cell Growth Factor (TCGF); Aldesleukin (pharmaceutical form); Lymphokine; Thymocyte Stimulating Factor; Recombinant Human Interleukin-2; rHuIL-2
EINECS	Contact for details

Quality Control

Our Human IL-2 is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is subjected to a comprehensive battery of tests including identity confirmation, purity analysis, and potency assays. Certificates of Analysis (COA) detailing specifications for purity (typically >95% by SDS-PAGE and HPLC), endotoxin levels, and biological activity are available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive) and light-sensitive; handle in a controlled environment to maintain integrity.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE)	> 95%
Purity (RP-HPLC)	> 95%
Biological Activity	Determined by cell proliferation assay
Endotoxin	< 1.0 EU/µg
Protein Content	Determined by UV absorbance
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.