Description

n-[(8-Fluoro-2,3-Dihydro-1-Methyl-5-Phenyl-1H-Benzo-1,4-Diazepin-2-Yl)Methyl]-3-Furamide is a high-purity, advanced pharmaceutical intermediate of significant interest in modern medicinal chemistry. This compound is valued for its role as a key synthetic building block in the development of novel therapeutic agents, particularly within the benzodiazepine class. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and new chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates targeting central nervous system (CNS) disorders.
• Contract Research & Manufacturing (CRAM): Used by CDMOs for the custom synthesis of complex molecules for clinical trial materials and niche therapeutic applications.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	n-[(8-Fluoro-2,3-Dihydro-1-Methyl-5-Phenyl-1H-Benzo-1,4-Diazepin-2-Yl)Methyl]-3-Furamide
CAS No.	94006-14-1
Molecular Formula	C22H20FN3O2
Molecular Weight	377.42 g/mol
Synonyms	8-Fluoro-2-[[(3-furoylamino)methyl]-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine; 3-Furamide, N-[(8-fluoro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-yl)methyl]-; 94006-14-1; 8-Fluoro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-2-methanamine, N-(3-furoyl)-; Benzodiazepine derivative, 8-fluoro-2-[[(3-furoylamino)methyl]-1-methyl-5-phenyl-2,3-dihydro-1H-
EINECS	Contact for details

Quality Control

Our n-[(8-Fluoro-2,3-Dihydro-1-Methyl-5-Phenyl-1H-Benzo-1,4-Diazepin-2-Yl)Methyl]-3-Furamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle under an inert atmosphere if necessary for prolonged operations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.