Description

6-Chloro-4-(2-Chlorophenyl)Quinazoline-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinazoline core structure. This compound is critical for the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in the production of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline-based drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for oncology and other therapeutic areas.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Organic Synthesis: Utilized in academic and industrial research for constructing complex heterocyclic compounds due to its reactive aldehyde and halogen functional groups.

Basic Information

Product Name	6-Chloro-4-(2-Chlorophenyl)Quinazoline-2-Carbaldehyde
CAS No.	93955-15-8
Molecular Formula	C15H8Cl2N2O
Molecular Weight	303.14 g/mol
Synonyms	2-Chloro-6-(2-chlorophenyl)quinazoline-4-carbaldehyde; 4-(2-Chlorophenyl)-6-chloroquinazoline-2-carboxaldehyde; 6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxaldehyde; 2-Quinazolinecarboxaldehyde, 6-chloro-4-(2-chlorophenyl)-; 93955-15-8; 4-(2-Chlorophenyl)-6-chloro-quinazoline-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-(2-Chlorophenyl)Quinazoline-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.