Description

7-Fluoro-2-Methyl-10H-Thieno[2,3-B][1,5]Benzodiazepin-4-Amine Monohydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 93923-93-4. This compound is of significant value for its role as a key building block in the synthesis of novel therapeutic agents, particularly within the central nervous system (CNS) drug discovery pipeline. It is primarily required by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in developing next-generation benzodiazepine analogs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and development of new benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of candidate drugs.
• CNS Drug Development: Serves as a key starting material for synthesizing potential therapeutics targeting neurological and psychiatric disorders.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for clinical trial material (CTM) manufacturing.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API production.
• Academic Research: Used in university and institutional labs for studying heterocyclic chemistry and drug-receptor interactions.

Basic Information

Item	Details
Product Name	7-Fluoro-2-Methyl-10H-Thieno[2,3-B][1,5]Benzodiazepin-4-Amine Monohydrochloride
CAS No.	93923-93-4
Molecular Formula	C12H11ClFN3S
Molecular Weight	283.75 g/mol
Synonyms	7-Fluoro-2-methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-amine hydrochloride; 7-Fluoro-2-methyl-4-amino-10H-thieno[2,3-b][1,5]benzodiazepine hydrochloride; 93923-93-4; Thienobenzodiazepine derivative; 4-Amino-7-fluoro-2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine monohydrochloride
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2-Methyl-10H-Thieno[2,3-B][1,5]Benzodiazepin-4-Amine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.