Description

Cholylsarcosine is a conjugated bile acid derivative formed from cholic acid and the amino acid sarcosine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a key intermediate in the synthesis of more complex bile acid analogs and its utility in studying bile acid transport and metabolism. It serves as a critical building block for researchers and manufacturers in the life sciences sector. Primary applications include its use as a reference standard, a synthetic precursor in drug discovery, and a biochemical tool for investigating hepatobiliary function.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of novel therapeutic bile acid conjugates and prodrugs.
• Biochemical Research: Used as a reference standard and probe in studies of bile acid transporters (e.g., ASBT, NTCP) and metabolic pathways.
• Diagnostic Agent Development: Serves as a precursor for developing contrast agents or biomarkers for liver and intestinal imaging.
• Academic & Industrial R&D: Employed in metabolic studies, enzyme inhibition assays, and membrane permeability research.
• Reference Standard: Provides a high-purity benchmark for quality control and analytical method development in laboratories.

Basic Information

Product Name	Cholylsarcosine
CAS No.	93790-70-6
Molecular Formula	C27H45NO6
Molecular Weight	479.65 g/mol
Synonyms	N-Choloylsarcosine; Sarcochenodeoxycholic Acid; 3α,7α,12α-Trihydroxy-5β-cholan-24-oyl-sarcosine; Cholylsarcosin; N-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]-N-methylglycine; Glycine, N-methyl-N-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-; Bile acid-sarcosine conjugate
EINECS	Contact for details

Quality Control

Our Cholylsarcosine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.